Congenital granular cell epulis: a case report with immunohistochemistry

Authors

  • Payman A. Rashid Department of Basic Sciences, College of Medicine, Hawler Medical University, Erbil, Iraq.
  • Jalal A. Jalal Department of Basic Sciences, College of Medicine, Hawler Medical University, Erbil, Iraq.
  • Muhammed Yakin School of Dentistry and Health Sciences, Charles Sturt University, Orange, NSW, Australia.

DOI:

https://doi.org/10.15218/edj.2021.07

Keywords:

Congenital granular cell epulis, congenital epulis, Histopathology, Immunohistochemistry

Abstract

Congenital granular cell epulis is a rare benign tumor of soft tissue in newborns. In most cases it arises from the anterior part of the maxillary alveolar ridge and is ten times more prevalent in females than males. We present a case report of a 2-month-old female infant, who presented with a mass on the gingival mucosa. The lesion was completely removed by simple excision. A final diagnosis of a congenital granular cell tumor was made by histologic and immunohistochemical examination.

References

Conrad R, Perez MC. Congenital granular cell epulis. Archives of pathology & laboratory medicine. 2014;138:128-31.

Childers EL, Fanburg-Smith JC. Congenital epulis of the newborn: 10 new cases of a rare oral tumor. Ann Diagn Pathol. 2011;15:157-61.

Lapid O, Shaco-Levy R, Krieger Y, Kachko L, Sagi A. Congenital epulis. Pediatrics. 2001;107:E22.

Allen CM, Bullerdiek J, Ro JY. Congenital granular cell epulis. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, editors. WHO Classification of Head and Neck Tumours. 4th ed. Lyon: IARC; 2017. p. 119.

Eghbalian F, Monsef A. Congenital epulis in the newborn, review of the literature and a case report. Journal of pediatric hematology/oncology.

;31:198-9.

O'Brian FV, Pielou WD. Congenital epulis: its natural history. Archives of disease in childhood. 1971;46:559-60.

Zuker RM, Buenechea R. Congenital epulis: review of the literature and case report. J Oral Maxillofac Surg. 1993;51:1040-3.

Vered M, Dobriyan A, Buchner A. Congenital granular cell epulis presents an immunohistochemical profile that distinguishes it from the granular cell tumor of the adult. Virchows Arch. 2009;454:303-10.

Vered M, Carpenter WM, Buchner A. Granular cell tumor of the oral cavity: updated immunohistochemical profile. J Oral Pathol Med. 2009;38:150-9.

Damm DD, Cibull ML, Geissler RH, Neville BW, Bowden CM, Lehmann JE. Investigation into the histogenesis of congenital epulis of the newborn.

Oral Surg Oral Med Oral Pathol. 1993;76:205-12.

Loyola AM, Gatti AF, Pinto DS, Jr., Mesquita RA. Alveolar and extra-alveolar granular cell lesions of the newborn: report of case and review of

literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84:668-71.

Nakata M, Anno K, Matsumori LT, Sumie M, Sase M, Nakano T, et al. Prenatal diagnosis of congenital epulis: a case report. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2002;20:627-9.

Kim ES, Gross TL. Prenatal ultrasound detection of a congenital epulis in a triple X female fetus: a case report. Prenatal diagnosis. 1999;19:774-6.

Downloads

Published

2021-07-30

How to Cite

1.
Rashid PA, Jalal JA, Yakin M. Congenital granular cell epulis: a case report with immunohistochemistry. EDJ [Internet]. 2021 Jul. 30 [cited 2024 Apr. 25];4(1):50-3. Available from: https://edj.hmu.edu.krd/index.php/journal/article/view/106

Issue

Section

Original Articles